US 11,788,984 B2
Glucose sensor electrode, preparation method therefor and use thereof
Chengyun Ning, Guangzhou (CN); Zhen'gao Wang, Guangzhou (CN); Peng Yu, Guangzhou (CN); Lei Qian, Guangzhou (CN); Zhengnan Zhou, Guangzhou (CN); Jun Xing, Guangzhou (CN); Junqi Chen, Guangzhou (CN); Lei Zhou, Guangzhou (CN); and Guoxin Tan, Guangzhou (CN)
Assigned to South China University of Technology, Guangdong (CN); and Guangdong University of Technology, Guangdong (CN)
Appl. No. 17/54,790
Filed by South China University of Technology, Guangzhou (CN); and Guangdong University of Technology, Guangzhou (CN)
PCT Filed Sep. 21, 2018, PCT No. PCT/CN2018/106842
§ 371(c)(1), (2) Date Nov. 12, 2020,
PCT Pub. No. WO2019/218562, PCT Pub. Date Nov. 21, 2019.
Claims priority of application No. 201810474956.3 (CN), filed on May 17, 2018.
Prior Publication US 2021/0215632 A1, Jul. 15, 2021
Int. Cl. G01N 27/327 (2006.01)
CPC G01N 27/3278 (2013.01) [G01N 27/3271 (2013.01)] 10 Claims
OG exemplary drawing
 
1. A glucose sensor electrode comprising a titanium electrode, whose surface is composed of a region formed by a nanoneedle titanium dioxide and a region formed by a nanocone-structured polypyrrole; the regions formed by the nanocone-structured polypyrrole each are adjacent to the regions formed by the nanoneedle titanium dioxide, which are located between the regions formed by the nanocone-structured polypyrrole; the regions formed by the nanocone-structured polypyrrole are grafted with an enzyme capable of detecting glucose; at least one of the region formed by the nanoneedle titanium dioxide and the region formed by the nanocone-structured polypyrrole is a micro-region.