US 11,787,830 B2
Crystalline solids of nicotinic acid mononucleotide and esters thereof and methods of making and use
Jonathan N. Kremsky, Worcester, MA (US); Bruce Szczepankiewicz, Worcester, MA (US); Karsten Koppetsch, Worcester, MA (US); Joseph Harris, Cambridge (GB); Mateusz Pitak, Cambridge (GB); and Martin Bates, Cambridge (GB)
Assigned to Metro International Biotech, LLC, Worcester, MA (US)
Filed by Metro International Biotech, LLC, Cambridge, MA (US)
Filed on Mar. 31, 2023, as Appl. No. 18/129,345.
Application 18/129,345 is a continuation of application No. PCT/US2022/031124, filed on May 26, 2022.
Claims priority of provisional application 63/193,905, filed on May 27, 2021.
Prior Publication US 2023/0257412 A1, Aug. 17, 2023
Int. Cl. C07H 19/048 (2006.01); A61K 31/706 (2006.01); C30B 7/02 (2006.01); C07H 1/06 (2006.01)
CPC C07H 19/048 (2013.01) [A61K 31/706 (2013.01); C07H 1/06 (2013.01); C30B 7/02 (2013.01)] 21 Claims
 
1. A crystalline solid comprising Compound 1:

OG Complex Work Unit Chemistry
having 2θ values 16.1, 20.1, and 24.5.