US 11,787,827 B2
Triaryl phosphine ligands, preparation method therefor, and use in catalyzing coupling reactions
Jicheng Shi, Guangdong (CN); and Fabin Zhou, Guangdong (CN)
Assigned to DONGGUAN STEPHEN CATALYST CO., LTD., Guangdong (CN)
Filed by DONGGUAN STEPHEN CATALYST CO., LTD., Guangdong (CN)
Filed on May 6, 2022, as Appl. No. 17/738,532.
Application 17/738,532 is a division of application No. 16/977,390, granted, now 11,420,987, previously published as PCT/CN2019/079966, filed on Mar. 28, 2019.
Claims priority of application No. 201810187687.2 (CN), filed on Mar. 7, 2018.
Prior Publication US 2022/0281901 A1, Sep. 8, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. C07F 9/50 (2006.01); B01J 31/24 (2006.01); C07F 15/00 (2006.01); C07F 15/04 (2006.01)
CPC C07F 9/5022 (2013.01) [B01J 31/2404 (2013.01); C07F 15/006 (2013.01); C07F 15/04 (2013.01)] 4 Claims
 
1. Triaryl phosphine ligands is selected from the group consisting of Ia and Ib:

OG Complex Work Unit Chemistry
wherein,
Ar is selected from 4-methoxyphenyl, 4-(dimethylamino)phenyl, 2-methoxyphenyl, 2-(dimethylamino)phenyl, 2,6-dimethoxyphenyl, 2,6-diisopropoxyphenyl, 2,6-bis(dimethylamino)phenyl, 2-methoxy-6-(dimethylamino)phenyl, or 2-methoxy-1-naphthyl;
R1 is selected from H, (C1-C6)alkyl, —O(C1-C6)alkoxy or —N(C1-C6)2 dialkylamino;
R2 and R3 are each independently selected from (C1-C10) alkyl, (C3-C10) cycloalkyl, (5-11 membered) heterocycloalkyl, (C6-C20) aryl, (C4-C20) hetero aryl or —CH2(C6-C10) arylmethylene, here (C3-C10) cycloalkyl, (5-11 membered) heterocycloalkyl, (C6-C20) aryl, (C4-C20) heteroaryl and —CH2(C6-C10)arylene groups can have 1 to 3 independently selected from (C1-C6)alkyl or —O(C1-C6)alkoxy, —N(C1-C6)2 substituents of dialkylamino groups, where the heteroatoms in the heteroaryl group are selected from O, N or S atom.