CPC C07D 471/04 (2013.01) [C07D 401/06 (2013.01); C07D 413/06 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01)] | 18 Claims |
1. A compound of Formula (I):
wherein
X is CH2 or O;
R2a and R2b are each independently selected from H and C1-4alkyl;
R3 is selected from:
(a) phenyl; phenyl substituted with one, two or three members each independently selected from: halo, C1-6alkyl, C1-6haloalkyl, C(CH3)2OH, OC1-6alkyl, OC1-6haloalkyl, SCH3, SF5, Si(CH3)3, N(CH3)2, C3-6cycloalkyl, OC3-6cycloalkyl, phenyl, O-phenyl, O-pyridyl and C3-6cycloalkyl substituted with CH3; and
(b) pyridyl substituted with C1-6alkyl; naphthyl;
R4 is selected from: H, F, and C1-3alkyl; and
R5a and R5b are each independently selected from H and CH3;
or a pharmaceutically acceptable salt, isotope, N-oxide, solvate, or stereoisomer thereof.
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