US 11,786,642 B2
In situ forming hemostatic form implants
Upma Sharma, Somerville, MA (US); Irina Gitlin, San Francisco, CA (US); Gregory T. Zugates, Chelmsford, MA (US); Adam Rago, Falmouth, MA (US); Parisa Zamiri, Brookline, MA (US); Rany Busold, Medford, MA (US); Toby Freyman, Waltham, MA (US); Robert J. Caulkins, Watertown, MA (US); Quynh P. Pham, Methuen, MA (US); Changcheng You, Burlington, MA (US); and Jeffrey D. Carbeck, Belmont, MA (US)
Assigned to Arsenal Medical, Inc., Watertown, MA (US)
Filed by Arsenal Medical Inc., Watertown, MA (US)
Filed on Aug. 7, 2020, as Appl. No. 16/987,754.
Application 16/987,754 is a continuation of application No. 15/642,968, filed on Jul. 6, 2017, granted, now 10,765,781.
Application 15/642,968 is a continuation of application No. 14/492,393, filed on Sep. 22, 2014, granted, now 9,700,656, issued on Jul. 11, 2017.
Application 14/492,393 is a continuation of application No. 13/209,020, filed on Aug. 12, 2011, granted, now 9,173,817, issued on Nov. 3, 2015.
Application 13/209,020 is a continuation in part of application No. 12/862,362, filed on Aug. 24, 2010, abandoned.
Claims priority of provisional application 61/368,095, filed on Jul. 27, 2010.
Claims priority of provisional application 61/236,314, filed on Aug. 24, 2009.
Prior Publication US 2020/0405921 A1, Dec. 31, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. A61F 2/02 (2006.01); A61L 31/06 (2006.01); A61J 1/20 (2006.01); A61L 27/18 (2006.01); A61L 27/56 (2006.01); A61L 27/58 (2006.01); A61L 31/14 (2006.01); A61M 37/00 (2006.01); A61B 17/12 (2006.01); C08L 63/00 (2006.01)
CPC A61L 31/06 (2013.01) [A61B 17/12031 (2013.01); A61B 17/12163 (2013.01); A61B 17/12186 (2013.01); A61J 1/2093 (2013.01); A61L 27/18 (2013.01); A61L 27/56 (2013.01); A61L 27/58 (2013.01); A61L 31/141 (2013.01); A61L 31/146 (2013.01); A61L 31/148 (2013.01); A61M 37/00 (2013.01); C08L 63/00 (2013.01); A61B 2017/12004 (2013.01); A61L 2400/04 (2013.01); A61L 2400/06 (2013.01); A61L 2400/18 (2013.01)] 26 Claims
OG exemplary drawing
 
1. A method of treating a patient by forming a polymer foam within a body cavity of the patient to control the flow of a bodily fluid, the method comprising:
i) combining a first component comprising a first polymer and a second component comprising a second polymer to form a polymer formulation; and
ii) introducing said polymer formulation and a blowing agent into the body cavity of the patient;
thereby foaming said polymer formulation; and
iii) crosslinking at least a portion of said first and second polymer of said polymer formulation to form a polymer foam in the body cavity of the patient;
wherein the polymer formulation undergoes a volume expansion greater than 12× upon foaming.