	US 11,786,587 B2
	Composition of subunit dengue vaccine
Yee-Shin Lin, Tainan (TW); Trai-Ming Yeh, Tainan (TW); Yung-Chun Chuang, Tainan (TW); Chia-Yi Yu, Tainan (TW); Hsin-Wei Chen, Miaoli County (TW); Shu-Wen Wan, Kaohsiung (TW); Shu-Ying Wang, Tainan (TW); Tzong-Shiann Ho, Tainan (TW); and Dar-Bin Shieh, Tainan (TW)
Assigned to NATIONAL CHENG KUNG UNIVERSITY, Tainan (TW)
Filed by National Cheng Kung University, Tainan (TW)
Filed on Jun. 19, 2020, as Appl. No. 16/906,134.
Claims priority of provisional application 62/863,278, filed on Jun. 19, 2019.
Prior Publication US 2020/0397884 A1, Dec. 24, 2020
Int. Cl. A61K 39/12 (2006.01); C12N 7/00 (2006.01); C07K 14/005 (2006.01)

CPC A61K 39/12 (2013.01) [C07K 14/005 (2013.01); C12N 7/00 (2013.01); C07K 2319/00 (2013.01); C12N 2770/24131 (2013.01)]

9 Claims

1. An immunogenic composition [of subunit dengue vaccine], comprising:

a fusion protein of truncated NS1 polypeptide of SEQ ID NOs: 5 and truncated NS3c polypeptide of SEQ ID NOs: 6, and optionally together with one or more pharmaceutically acceptable carriers and/or adjuvants.