	US 11,786,568 B2
	*Strain of caucasus yoghurt lactobacillus* MSR101 and use thereof**
Liqing Zhao, Guangdong (CN); and Muhammad Shahid Riza Rajoka, Guangdog (CN)
Assigned to SHENZHEN UNIVERSITY, Guangdong (CN)
Appl. No. 17/288,315
Filed by SHENZHEN UNIVERSITY, Guangdong (CN)
PCT Filed Mar. 18, 2020, PCT No. PCT/CN2020/079861 § 371(c)(1), (2) Date Apr. 23, 2021, PCT Pub. No. WO2020/228410, PCT Pub. Date Nov. 19, 2020.
Claims priority of application No. 201910388000.6 (CN), filed on May 10, 2019.
Prior Publication US 2022/0056401 A1, Feb. 24, 2022
Int. Cl. A61K 35/747 (2015.01); A61P 3/00 (2006.01); A61K 35/00 (2006.01); C12N 1/24 (2006.01); C12R 1/225 (2006.01)

CPC A61K 35/747 (2013.01) [A61K 35/00 (2013.01); A61P 3/00 (2018.01); C12N 1/24 (2013.01); A61K 2035/115 (2013.01); C12R 2001/225 (2021.05)]

1 Claim

1. A method for lowering concentration of cholesterol in a subject in need thereof, comprising a step of administering a strain of Lactobacillus kefiri MSR101 to the subject, wherein the strain of Lactobacillus kefiri MSR101 is deposited with the China General Microbiological Culture Collection under the accession number of CGMCC No. 17506, the strain of Lactobacillus kefiri MSR101 comprising a 16s RNA gene sequence of SEQ ID NO: 1, and primers used to amplify the 16s rDNA sequence are 5″-AGAGTTTGATCCTGGCTC AG-3″ (SEQ ID NO. 2) and reverse 5″-CCGTCAATTCCTTTGAGTTT-3″ (SEQ ID NO. 3).