CPC A61K 31/502 (2013.01) [A61K 9/5161 (2013.01); A61K 9/5192 (2013.01); A61K 31/704 (2013.01); A61P 35/00 (2018.01); B82Y 5/00 (2013.01); B82Y 40/00 (2013.01)] | 5 Claims |
1. An anti-tumor nano-drug delivery system containing hydralazine (HDZ), wherein the anti-tumor nano-drug delivery system is hydralazine-nanoparticles (H-NPs) with a hydrophobic core of both doxorubicin and the hydralazine and is assembled by Dex-hyd-DOX/cRGD and the hydralazine together; and the Dex-hyd-DOX/cRGD is a cRGD polypeptide dextran-doxorubicin prodrug with pH responsiveness and tumor targeting.
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