US 11,786,292 B2
Integrated nasal nerve detector ablation-apparatus, nasal nerve locator, and methods of use
William Jason Fox, San Mateo, CA (US); David Moosavi, Redwood City, CA (US); Mojgan Saadat, Atherton, CA (US); Vahid Saadat, Atherton, CA (US); Caroline Sobek, Redwood City, CA (US); and Neekon Saadat, Redwood City, CA (US)
Assigned to Arrinex, Inc., Redwood City, CA (US)
Filed by Arrinex, Inc., Redwood City, CA (US)
Filed on Jan. 14, 2022, as Appl. No. 17/575,889.
Application 17/575,889 is a continuation of application No. 15/786,306, filed on Oct. 17, 2017, granted, now 11,253,312.
Claims priority of provisional application 62/408,920, filed on Oct. 17, 2016.
Prior Publication US 2022/0133395 A1, May 5, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 18/14 (2006.01); A61B 18/02 (2006.01); A61B 5/00 (2006.01); A61B 5/06 (2006.01); A61B 5/01 (2006.01); A61B 5/0538 (2021.01); A61B 18/00 (2006.01); A61B 17/24 (2006.01); A61B 34/20 (2016.01); A61N 1/36 (2006.01)
CPC A61B 18/1442 (2013.01) [A61B 5/01 (2013.01); A61B 5/0538 (2013.01); A61B 5/065 (2013.01); A61B 5/4836 (2013.01); A61B 5/4893 (2013.01); A61B 5/6819 (2013.01); A61B 5/6877 (2013.01); A61B 18/02 (2013.01); A61B 18/1492 (2013.01); A61B 17/24 (2013.01); A61B 18/1485 (2013.01); A61B 34/20 (2016.02); A61B 2018/0022 (2013.01); A61B 2018/00327 (2013.01); A61B 2018/00434 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00696 (2013.01); A61B 2018/00791 (2013.01); A61B 2018/00875 (2013.01); A61B 2018/00904 (2013.01); A61B 2018/00982 (2013.01); A61B 2018/0212 (2013.01); A61B 2018/1495 (2013.01); A61B 2562/0209 (2013.01); A61N 1/36 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A system for ablating at least one nasal nerve associated with at least one symptom of rhinitis, the system comprising:
a probe shaft having a proximal end and a distal end;
an expandable ablation member permanently coupled to the distal end of the probe shaft;
at least two electrodes disposed on a distal tip that is releasably coupled to the probe shaft, the at least two electrodes electrically coupled to an electrical source, wherein the at least two electrodes are configured to electrically stimulate at least one nasal nerve underlying a nasal surface in contact with the least two electrodes in response to an electrical current generated by the electrical source, wherein the least two electrodes are configured to detect a parameter indicative of a physiologic response to the electrical current; and
a processor operatively coupled to the electrical source, wherein the processor is configured to:
control the electrical current generated by the electrical source,
receive the parameter indicative of the physiologic response to the electrical current, wherein the physiologic response is at least one physiologic response selected from a group consisting of: a change in nasal secretion and a change in arterial blood flow, and
control, based on the parameter, the electrical current generated by the electrical source to cause the least two electrodes to ablate the at least one nasal nerve underlying the nasal surface to reduce the at least one symptom associated with rhinitis.