US 11,755,922 B2
On-chip nanoscale storage system using chimeric DNA
Olgica Milenkovic, Urbana, IL (US); Nagendra Athreya, Urbana, IL (US); Apratim Khandelwal, Champaign, IL (US); Jean-Pierre Leburton, Urbana, IL (US); Xiuling Li, Champaign, IL (US); Charles Schroeder, Champaign, IL (US); SeyedKasra Tabatabaei, Urbana, IL (US); and Bo Li, Champaign, IL (US)
Assigned to THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, Urbana, IL (US)
Filed by The Board of Trustees of the University of Illinois, Urbana, IL (US)
Filed on Oct. 4, 2019, as Appl. No. 16/593,450.
Prior Publication US 2021/0103824 A1, Apr. 8, 2021
Int. Cl. G06N 3/00 (2023.01); G06N 3/12 (2023.01); G06N 3/123 (2023.01); C12N 7/00 (2006.01)
CPC G06N 3/123 (2013.01) [C12N 7/00 (2013.01); C12N 2310/3181 (2013.01); C12N 2310/52 (2013.01); C12N 2795/00031 (2013.01); C12N 2795/00042 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A deoxyribonucleic acid (DNA)-based data storage element comprising:
a DNA backbone, and multiple non-natural nucleic acids bioconjugated to the DNA backbone, wherein the multiple non-natural nucleic acids are arranged in a plurality of blocks, wherein each block corresponds to an alphabet symbol of an alphabet, wherein the alphabet comprises at least n4 alphabet symbols, where n is greater than 1, wherein at least a portion of the blocks comprise nonuniform length repetition patterns;
wherein each of the multiple non-natural nucleic acids independently comprise a triazole moiety linked to a non-natural functional group.