CPC C07K 16/2851 (2013.01) [C07K 2317/565 (2013.01)] | 131 Claims |
1. A Dectin-2 binding agent comprising an immunoglobulin heavy chain variable region polypeptide and an immunoglobulin light chain variable region polypeptide, wherein, according to Kabat numbering:
the immunoglobulin heavy chain variable region polypeptide comprises a complementarity determining region 1 (HCDR1) comprising SEQ ID NO: 18, a complementarity determining region 2 (HCDR2) comprising SEQ ID NO: 49, and a complementarity determining region 3 (HCDR3) comprising SEQ ID NO: 83, and
the immunoglobulin light chain variable region polypeptide comprises a complementarity determining region 1 (LCDR1) comprising SEQ ID NO: 117, a complementarity determining region 2 (LCDR2) SEQ ID NO: 138, and a complementarity determining region 3 (LCDR3) comprising SEQ ID NO: 150.
|