US 11,753,472 B2
Antibodies directed against T cell immunoglobulin and mucin protein 3 (TIM-3)
David J. King, Encinitas, CA (US); Marilyn Kehry, San Diego, CA (US); Srimoyee Ghosh, Waltham, MA (US); and Baochuan Huang, Waltham, MA (US)
Assigned to Tesaro, Inc., Wilmington, DE (US); and Anaptysbio, Inc., San Diego, CA (US)
Filed by AnaptysBio, Inc., San Diego, CA (US); and Tesaro, Inc., Waltham, MA (US)
Filed on Oct. 27, 2021, as Appl. No. 17/512,257.
Application 17/512,257 is a continuation of application No. 16/346,463, abandoned, previously published as PCT/US2017/059619, filed on Nov. 1, 2017.
Claims priority of provisional application 62/427,775, filed on Nov. 29, 2016.
Claims priority of provisional application 62/416,131, filed on Nov. 1, 2016.
Prior Publication US 2022/0169734 A1, Jun. 2, 2022
Int. Cl. C07K 16/28 (2006.01); A61P 37/06 (2006.01); A61P 35/02 (2006.01); A61K 45/06 (2006.01)
CPC C07K 16/2818 (2013.01) [A61P 35/02 (2018.01); A61P 37/06 (2018.01); C07K 16/2803 (2013.01); C07K 16/2827 (2013.01); A61K 45/06 (2013.01); C07K 2317/41 (2013.01); C07K 2317/524 (2013.01); C07K 2317/53 (2013.01); C07K 2317/70 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); Y02A 50/30 (2018.01)] 19 Claims
 
1. An antibody that binds T Cell Immunoglobulin and Mucin Protein 3 (TIM-3), said antibody comprising: a heavy chain polypeptide comprising the amino acid sequence of SEQ ID NO: 1; and a light chain polypeptide comprising the amino acid sequence of SEQ ID NO: 2.