CPC C07J 51/00 (2013.01) [C07F 9/09 (2013.01); C07F 9/095 (2013.01)] | 7 Claims |
1. A process for phosphorylating tocopherol, comprising the steps of:
(a) mixing the tocopherol and P4O10 until the mixture achieves an exothermic reaction temperature, said temperature being the temperature at which the chemical reaction between the tocopherol and P4O10 commences to release heat into the mixture;
(b) allowing the reaction mixture of step (a) to react until the exothermic reaction is complete, wherein the exothermic reaction is complete when the temperature of the mixture comprising the chemical reaction between the tocopherol and P4O10 begins to fall;
(c) cooling the reaction mixture of step (b) to at least 80° C.; and
(d) hydrolysing the reaction mixture of step (c), wherein hydrolysis is conducted for 30 to 90 minutes.
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