	US 11,752,178 B2
	Methods for the isolation of microbes with enhanced persistance and compositions with such microbes
Robert Hutkins, Lincoln, NE (US); Car Reen Kok, Lincoln, NE (US); and Maria X. Maldonado-Gomez, Sacramento, CA (US)
Assigned to NUtech Ventures, Lincoln, NE (US)
Filed by NUtech Ventures, Lincoln, NE (US)
Filed on Apr. 17, 2020, as Appl. No. 16/852,236.
Claims priority of provisional application 63/000,915, filed on Mar. 27, 2020.
Claims priority of provisional application 62/881,911, filed on Aug. 1, 2019.
Claims priority of provisional application 62/835,279, filed on Apr. 17, 2019.
Prior Publication US 2021/0069266 A1, Mar. 11, 2021
Int. Cl. A23L 33/135 (2016.01); A61K 35/745 (2015.01); A23L 33/21 (2016.01); A61K 47/36 (2006.01); A61K 9/19 (2006.01)

CPC A61K 35/745 (2013.01) [A23L 33/135 (2016.08); A23L 33/21 (2016.08); A61K 47/36 (2013.01); A23Y 2300/55 (2013.01); A23Y 2300/59 (2013.01); A61K 9/19 (2013.01)]

17 Claims

1. A synbiotic composition comprising:

a probiotic species selected from the group consisting of B. pseudocatenulatum, B. longum subsp. longum, and any combination thereof, wherein the B. longum subsp. longum has a nucleotide sequence having at least 99% sequence identity to SEQ ID NO. 5; and

a prebiotic comprising an amount of xylooligosaccharide.