	US 11,752,175 B2
	Compositions and methods for glaucoma
John T. G. Pena, New York, NY (US); James Murray Mitchell, Danville, CA (US); and Harmon Lawrence Remmel, New York, NY (US)
Assigned to Cornell University, Ithaca, NY (US)
Filed by AUFBAU MEDICAL INNOVATIONS LIMITED, Dublin (IE); and CORNELL UNIVERSITY, Ithaca, NY (US)
Filed on Sep. 21, 2019, as Appl. No. 16/578,320.
Claims priority of provisional application 62/734,699, filed on Sep. 21, 2018.
Prior Publication US 2020/0121724 A1, Apr. 23, 2020
Int. Cl. A61K 35/30 (2015.01); C12N 5/079 (2010.01); A61K 9/127 (2006.01)

CPC A61K 35/30 (2013.01) [A61K 9/1271 (2013.01); C12N 5/0621 (2013.01); C12N 2509/00 (2013.01); C12N 2521/00 (2013.01); C12N 2525/00 (2013.01); C12N 2527/00 (2013.01)]

9 Claims

1. A composition, consisting of extracellular vesicle aggregate complexes isolated from a glaucoma ocular humor, wherein the extracellular vesicle aggregate complexes are present in native glaucoma ocular humor, and wherein the extracellular aggregate complexes have at least 10 extracellular vesicles.