CPC A61K 31/485 (2013.01) [A61K 31/137 (2013.01)] | 14 Claims |
1. A method of using a non-competitive N-methyl D-aspartate (NMDA) receptor antagonist to treat major depressive disorder, comprising administering, no more than twice daily, a combination of 105 mg of bupropion hydrochloride and 45 mg of dextromethorphan hydrobromide to a human patient who is experiencing major depressive disorder, wherein the human patient has a history of drug abuse, and wherein the human patient does not experience dissociation.
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