	US 11,752,116 B2
	Method of viral inhibition
Johanna Elisabeth Fraser, Warranwood (AU); David Andrew Jans, Caulfield South (AU); and Kylie Michelle Wagstaff, Cockatoo (AU)
Assigned to Monash University, Clayton (AU)
Filed by Monash University, Clayton (AU)
Filed on Apr. 19, 2021, as Appl. No. 17/233,887.
Application 17/233,887 is a continuation of application No. 14/785,059, granted, now 11,007,160, previously published as PCT/AU2014/050017, filed on Apr. 16, 2014.
Claims priority of application No. 2013901525 (AU), filed on Apr. 16, 2013.
Prior Publication US 2022/0016057 A1, Jan. 20, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/167 (2006.01); A61K 31/203 (2006.01)

CPC A61K 31/167 (2013.01) [A61K 31/203 (2013.01); Y02A 50/30 (2018.01)]

12 Claims

1. A method of preventing or delaying the onset of one or more symptoms of dengue virus (DENV) in a subject at risk of being exposed to DENV, comprising:

administering a daily dose of N-(4-hydroxyphenyl) retinamide (4-HPR) to the subject of up to 4,000 mg/m²/day during a period of time in which the subject is at risk of exposure, wherein the subject is not being administered an anti-viral agent other than 4-HPR.