US 11,752,079 B2
Antimicrobial mixture containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and a diol, and cosmetic composition containing same
Florence Menard-Szczebara, Chevilly Larue (FR); Sylvie Cupferman, Chevilly Larue (FR); Julien Galvan, Chevilly Larue (FR); and Véronique Chevalier, Chevilly Larue (FR)
Assigned to L'OREAL, Paris (FR)
Appl. No. 16/626,051
Filed by L'OREAL, Paris (FR)
PCT Filed Jun. 27, 2018, PCT No. PCT/EP2018/067298
§ 371(c)(1), (2) Date Dec. 23, 2019,
PCT Pub. No. WO2019/002392, PCT Pub. Date Jan. 3, 2019.
Claims priority of application No. 1756159 (FR), filed on Jun. 30, 2017; application No. 1756165 (FR), filed on Jun. 30, 2017; and application No. 1760568 (FR), filed on Nov. 10, 2017.
Prior Publication US 2021/0205192 A1, Jul. 8, 2021
Int. Cl. A61K 8/35 (2006.01); A61K 8/34 (2006.01); A61K 8/06 (2006.01); A61Q 19/00 (2006.01)
CPC A61K 8/35 (2013.01) [A61K 8/062 (2013.01); A61K 8/345 (2013.01); A61Q 19/00 (2013.01); A61K 2800/524 (2013.01)] 15 Claims
 
1. An antimicrobial mixture comprising 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and 1,3-propanediol, wherein the 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and 1,3-propanediol are present in the mixture in an amount such that the 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one/1,3-propanediol weight ratio ranges from 0.02 to 0.15 and wherein the antimicrobial mixture exhibits synergistic inhibitory activity.