US 11,751,769 B2
Systems and methods for assessing diabetic circulatory complications
David Cuccia, Costa Mesa, CA (US); and Amaan Mazhar, Corona Del Mar, CA (US)
Assigned to MODULATED IMAGING, INC., Irvine, CA (US)
Filed by MODULATED IMAGING, INC., Irvine, CA (US)
Filed on Sep. 9, 2019, as Appl. No. 16/565,045.
Application 16/565,045 is a continuation of application No. PCT/US2018/023856, filed on Mar. 22, 2018.
Claims priority of provisional application 62/475,059, filed on Mar. 22, 2017.
Prior Publication US 2020/0107732 A1, Apr. 9, 2020
Int. Cl. A61B 5/02 (2006.01); A61B 5/00 (2006.01); A61B 5/145 (2006.01); A61B 5/1455 (2006.01)
CPC A61B 5/02007 (2013.01) [A61B 5/0064 (2013.01); A61B 5/0077 (2013.01); A61B 5/14546 (2013.01); A61B 5/14551 (2013.01); A61B 5/486 (2013.01); A61B 5/7275 (2013.01); A61B 5/748 (2013.01); A61B 5/7425 (2013.01); A61B 2562/223 (2013.01)] 12 Claims
OG exemplary drawing
 
1. An optical measurement system to extract the levels of hemoglobin and oxygen saturation in different layers of tissues, comprising:
a light source configured to illuminate an area of tissue of a patient with light signals comprising a plurality of illumination wavelengths and a spatially-structured light pattern;
a detector configured to coincidentally capture light signals reflecting from a first layer of tissue within the illumined area of tissue and reflecting from a second layer of tissue within the illuminated area of tissue at the plurality of illumination wavelengths;
a processor configured to compute, within the illuminated area of the tissue from the captured light signals, tissue oxygen saturation levels and layer of tissue specific hemoglobin levels, and estimate the severity of circulatory complications due to diabetes of the illuminated area of tissue as a function of the determined tissue oxygen saturation levels and layer of tissue specific hemoglobin levels in each of the first and second layers of tissue within the illuminated area of tissue of the patient; and
a display or communication device configured to display or report the estimated severity of circulatory complications within the illuminated area of tissue.