US 11,751,567 B2
Steroidal piperidone derivative, synthesis method, and use thereof
Baojun Shi, Xianyang (CN); Weiqi Jiang, Xianyang (CN); Shichuang Ma, Xianyang (CN); Yuxiao Hu, Xianyang (CN); and Qiangping Wang, Xianyang (CN)
Filed by NORTHWEST A&F UNIVERSITY, Xianyang (CN)
Filed on Sep. 23, 2022, as Appl. No. 17/951,129.
Claims priority of application No. 202111114215.2 (CN), filed on Sep. 23, 2021.
Prior Publication US 2023/0105315 A1, Apr. 6, 2023
Int. Cl. A01N 43/42 (2006.01); A01P 7/04 (2006.01); C07J 73/00 (2006.01)
CPC A01N 43/42 (2013.01) [A01P 7/04 (2021.08); C07J 73/005 (2013.01)] 9 Claims
 
1. A steroidal piperidone derivative with a chemical structure shown in a general formula (1) or a general formula (2),

OG Complex Work Unit Chemistry
wherein R is (5g) or (6g):

OG Complex Work Unit Chemistry
R1 is a substituent at an ortho position, a meta position, or a para position;
R2 and R3 are each 2,3-substituted, 2,4-substituted, 2,5-substituted, 2,6-substituted, 3,4-substituted, 3,5-substituted, 3,6-substituted, 4,5-substituted, 4,6-substituted, or 5,6-substituted; and
substituents of R1, R2, and R3 are each one selected from the group consisting of halogen, trifluoromethyl, methyl, nitro, and methoxy.