CPC G16B 20/00 (2019.02) [G16B 35/10 (2019.02)] | 23 Claims |
1. A method comprising steps of:
querying a set of nucleic acid sequences, each of which is found in a fungal strain and comprises a biosynthetic gene cluster; and
identifying within at least one of the fungal nucleic acid sequences an embedded target gene (ETaG) sequence characterized in that it:
is not required for or is not involved in the biosynthesis of the product of the biosynthetic gene cluster;
is within a proximity zone relative to at least one gene in the cluster;
is homologous to a mammalian nucleic acid sequence; and
is optionally co-regulated with at least one biosynthetic gene in the cluster.
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