CPC G01N 33/57496 (2013.01) [C07K 16/22 (2013.01); C07K 16/30 (2013.01); C07K 2317/20 (2013.01); C07K 2317/34 (2013.01); C07K 2317/92 (2013.01); G01N 2333/485 (2013.01)] | 20 Claims |
1. An antibody or antibody fragment capable of specifically binding to amino acids 156-169 of SEQ ID NO: 1, wherein the antibody comprises a heavy chain comprising the following hypervariable regions (HVRs):
(a) an HVR-H1 comprising SEQ ID NO: 18;
(b) an HVR-H2 comprising SEQ ID NO: 19; and
(c) an HVR-H3 comprising SEQ ID NO: 20; and
wherein the antibody or antibody fragment further comprises a light chain comprising the following HVRs:
(h) an HVR-L1 comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 25 and SEQ ID NO: 26;
(i) an HVR-L2 comprising SEQ ID NO: 27; and
(j) an HVR-L3 comprising SEQ ID NO: 28.
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