US 11,747,323 B2
Methods and systems for analyte detection and analysis
Kristopher Barbee, Pleasanton, CA (US); Nathan Beckett, Oakland, CA (US); Denis Pristinski, Dublin, CA (US); Derek Schulte, Los Angeles, CA (US); Avishai Bartov, Hod-Hasharon (IL); Jamie Sullivan, Eugene, OR (US); Dumitru Brinza, Montara, CA (US); Abizar Lakdawalla, Los Altos Hills, CA (US); Steven Menchen, Fremont, CA (US); Gilad Almogy, Palo Alto, CA (US); and Mark Pratt, Bozeman, MT (US)
Assigned to ULTIMA GENOMICS, INC., Newark, CA (US)
Filed by Ultima Genomics, Inc., Newark, CA (US)
Filed on Oct. 7, 2022, as Appl. No. 17/962,163.
Application 17/962,163 is a continuation of application No. 16/862,196, filed on Apr. 29, 2020, granted, now 11,499,962.
Application 16/862,196 is a continuation of application No. PCT/US2018/061598, filed on Nov. 16, 2018.
Application PCT/US2018/061598 is a continuation in part of application No. 15/974,441, filed on May 8, 2018, granted, now 10,267,790, issued on Apr. 23, 2019.
Application 15/974,441 is a continuation in part of application No. 15/974,364, filed on May 8, 2018, granted, now 10,344,328, issued on Jul. 9, 2019.
Application 15/974,364 is a continuation in part of application No. 15/974,543, filed on May 8, 2018, granted, now 10,273,528, issued on Apr. 30, 2019.
Claims priority of provisional application 62/664,049, filed on Apr. 27, 2018.
Claims priority of provisional application 62/623,743, filed on Jan. 30, 2018.
Claims priority of provisional application 62/588,139, filed on Nov. 17, 2017.
Prior Publication US 2023/0152300 A1, May 18, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 33/49 (2006.01); G01N 1/02 (2006.01); G01Q 10/04 (2010.01); G01N 1/22 (2006.01)
CPC G01N 33/492 (2013.01) [G01N 1/02 (2013.01); G01Q 10/04 (2013.01); G01N 2001/2291 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method for analyte detection or analysis, comprising:
(a) rotating a substrate about a rotational axis, the substrate comprising a plurality of analytes immobilized thereon; and
(b) using a detector comprising one or more sensors to image the substrate during the rotating to detect a plurality of signals from the plurality of analytes, wherein an imaging field of view comprises at least a first region and a second region which are disposed at different radial distances with respect to the rotational axis, wherein the one or more sensors comprises a plurality of segments, wherein a first segment and a second segment of the plurality of segments (i) image the first region and the second region, respectively, and (ii) are clocked independently with respect to each other based at least in part on different tangential velocities of the first region and the second region, respectively, at the different radial distances.