CPC G01N 30/468 (2013.01) [G01N 30/463 (2013.01); G01N 2030/027 (2013.01)] | 12 Claims |
1. A multidimensional liquid chromatography system, comprising:
a switching valve operable in at least two valve states;
a detector in communication with the switching valve through a first fluidic path defined by tubing having a first end coupled to a port of the switching valve and a second end coupled to the detector for coupling the switching valve to the detector;
a routing valve in communication with the switching valve through a second fluidic path defined by tubing having a first end coupled to another port of the switching valve and a second end coupled to a first port of the routing valve for coupling the switching valve to the routing valve; and
a first fluidic loop valve in communication with the routing valve through a third fluidic path defined by tubing having a first end coupled to a second port of the routing valve and a second end coupled to the first fluidic loop valve for coupling the routing valve to the first fluidic loop valve,
wherein a volume of the first fluidic path is substantially equal to a sum of a volume of the second fluidic path and a volume of the third fluidic path.
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