US 11,747,276 B2
Interferometric detection and quantification system and methods of use in agriculture
Ron Levin, Valdosta, GA (US); Clinton Beeland, Valdosta, GA (US); James LeFiles, Valdosta, GA (US); Joseph Egan, Atlanta, GA (US); Timothy Zollers, Atlanta, GA (US); and Jacob Thompson, Atlanta, GA (US)
Assigned to SALVUS, LLC, Valdosta, GA (US)
Filed by Salvus, LLC, Valdosta, GA (US)
Filed on Sep. 20, 2021, as Appl. No. 17/448,067.
Claims priority of provisional application 63/080,219, filed on Sep. 18, 2020.
Prior Publication US 2022/0091029 A1, Mar. 24, 2022
Int. Cl. G01J 3/45 (2006.01); G01N 21/45 (2006.01); G01N 33/53 (2006.01); G01N 21/77 (2006.01)
CPC G01N 21/45 (2013.01) [G01J 3/45 (2013.01); G01N 21/77 (2013.01); G01N 33/5308 (2013.01); G01N 2021/7779 (2013.01)] 21 Claims
OG exemplary drawing
 
1. A portable interferometric system for detection and quantification of analyte within an agricultural test sample composition, the system comprising:
an optical assembly unit, the optical assembly unit comprising a light unit and a detector unit each adapted to fit within a portable housing unit;
a cartridge system adapted to be inserted in the housing unit and removed after one or more uses, the cartridge system comprising:
an interferometric chip including one or more waveguide channels having a sensing layer thereon, the sensing layer adapted to selectively bind or otherwise be selectively disturbed by one or more analytes within the agricultural test sample composition; and
a flow cell wafer; and
a cartridge housing enclosing the interferometric chip and flow cell wafer; and
an alignment means for aligning the cartridge system within a cartridge recess in the optical assembly unit upon insertion thereby providing optical and microfluidic alignment of the interferometric chip and flow cell wafer.