US 11,746,370 B2
Methods and compositions for assessing and treating intraocular diseases and disorders
Lai Wei, Zhuhai (CN)
Assigned to SMILEBIOTEK ZHUHAI LIMITED, Zhuhai (CN)
Appl. No. 16/758,365
Filed by SMILEBIOTEK ZHUHAI LIMITED, Zhuhai (CN)
PCT Filed Oct. 26, 2018, PCT No. PCT/CN2018/112022
§ 371(c)(1), (2) Date Apr. 22, 2020,
PCT Pub. No. WO2019/080916, PCT Pub. Date May 2, 2019.
Claims priority of application No. 201711017087.3 (CN), filed on Oct. 26, 2017.
Prior Publication US 2020/0340030 A1, Oct. 29, 2020
Int. Cl. C12Q 1/04 (2006.01); C12Q 1/6888 (2018.01)
CPC C12Q 1/04 (2013.01) [C12Q 1/6888 (2013.01); G01N 2333/32 (2013.01); G01N 2800/16 (2013.01)] 19 Claims
 
1. A kit or device for assessing age-related macular degeneration (AMD) in a subject, which kit or device comprises reagents for assessing the presence, absence, quantity, and/or the infectious status of Bacillus megaterium in an intraocular space, cavity or sample of a subject, wherein the etiology of said AMD comprises infection of said Bacillus megaterium in said intraocular space or cavity of said subject, and which kit or device further comprises a tool for obtaining a sample from said intraocular space or cavity of said subject.