US 11,746,345 B2
Method for producing an L-amino acid using a bacterium of the family Enterobacteriaceae having an attenuated expression of a gshA gene
Valery Vasilievich Samsonov, Moscow (RU); Natalia Sergeevna Eremina, Moscow (RU); and Natalia Viktorovna Stoynova, Moscow (RU)
Assigned to AJINOMOTO CO., INC., Tokyo (JP)
Filed by AJINOMOTO CO., INC., Tokyo (JP)
Filed on May 26, 2016, as Appl. No. 15/165,606.
Claims priority of application No. RU2015120052 (RU), filed on May 28, 2015.
Prior Publication US 2016/0348089 A1, Dec. 1, 2016
Int. Cl. C12N 9/00 (2006.01); C12P 13/08 (2006.01); C12P 13/04 (2006.01); C12N 15/52 (2006.01); C12P 13/06 (2006.01); C12P 13/10 (2006.01); C12P 13/12 (2006.01); C12P 13/14 (2006.01); C12P 13/22 (2006.01); C12P 13/24 (2006.01)
CPC C12N 9/93 (2013.01) [C12N 15/52 (2013.01); C12P 13/04 (2013.01); C12P 13/06 (2013.01); C12P 13/08 (2013.01); C12P 13/10 (2013.01); C12P 13/12 (2013.01); C12P 13/14 (2013.01); C12P 13/222 (2013.01); C12P 13/227 (2013.01); C12P 13/24 (2013.01); C12Y 603/02002 (2013.01)] 11 Claims
 
1. A method for producing an L-amino acid comprising:
(i) cultivating an L-amino acid-producing bacterium of the family Enterobacteriaceae in a culture medium to produce the L-amino acid in the culture medium, the bacterium, or both; and
(ii) collecting said L-amino acid from the culture medium, the bacterium, or both, wherein said bacterium has been modified to attenuate expression of a gshA gene, and wherein said L-amino acid is a branched-chain L-amino acid.