US 11,745,181 B2
Devices and methods for bioassay
Deepak Solomon, San Diego, CA (US)
Assigned to UNCHAINED LABS, Pleasanton, CA (US)
Appl. No. 16/637,406
Filed by Unchained Labs, Pleasanton, CA (US)
PCT Filed Aug. 8, 2018, PCT No. PCT/US2018/045793
§ 371(c)(1), (2) Date Feb. 7, 2020,
PCT Pub. No. WO2019/032690, PCT Pub. Date Feb. 14, 2019.
Claims priority of provisional application 62/543,324, filed on Aug. 9, 2017.
Prior Publication US 2020/0179930 A1, Jun. 11, 2020
Int. Cl. B01L 3/00 (2006.01); G01N 33/50 (2006.01)
CPC B01L 3/502761 (2013.01) [B01L 3/502738 (2013.01); G01N 33/5044 (2013.01); B01L 2200/0647 (2013.01); B01L 2200/16 (2013.01); B01L 2300/041 (2013.01); B01L 2300/06 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0883 (2013.01); B01L 2300/12 (2013.01); B01L 2300/168 (2013.01); B01L 2400/06 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A fluidic device for bioassay comprising:
a substrate with a first surface and a second surface; said substrate having a fluidic chamber formed on the first surface; wherein the fluidic chamber comprises:
a sample chamber in fluid communication with an air valve;
a bioassay channel having a first end in fluid communication with the sample chamber and a second end in fluid communication with a first outlet chamber, said bioassay channel comprising a first and opposing second linear array of pillars formed proximal to each of a first lateral wall and opposing second lateral wall of the bioassay channel; and
a plurality of ports formed through the substrate from the second surface comprising:
a first fluidic device port providing external fluid communication to the air valve;
a second fluidic device port providing external fluid communication to the sample chamber; and
a third fluidic device port providing external fluid communication to the first outlet chamber.