US 11,745,165 B2
Supramolecular filamentous assemblies for protein purification
Honggang Cui, Lutherville, MD (US); Yi Li, Baltimore, MD (US); Lye Lin Lock, Maynard, MA (US); XuanKuo Xu, Boxborough, MA (US); and Zhengjian Li, Sudbury, MA (US)
Assigned to THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US); and BRISTOL-MYERS SQUIBB COMPANY, Princeton, NJ (US)
Appl. No. 16/639,763
Filed by THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US); and BRISTOL-MYERS SQUIBB COMPANY, Princeton, NJ (US)
PCT Filed Aug. 17, 2018, PCT No. PCT/US2018/046924
§ 371(c)(1), (2) Date Feb. 18, 2020,
PCT Pub. No. WO2019/036631, PCT Pub. Date Feb. 21, 2019.
Claims priority of provisional application 62/547,256, filed on Aug. 18, 2017.
Prior Publication US 2020/0197902 A1, Jun. 25, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 1/22 (2006.01); C07K 7/08 (2006.01); C07K 14/31 (2006.01); B01J 20/24 (2006.01); B01D 15/38 (2006.01); B01J 20/28 (2006.01); B01J 20/34 (2006.01); C07K 16/06 (2006.01)
CPC B01J 20/24 (2013.01) [B01D 15/3809 (2013.01); B01J 20/28023 (2013.01); B01J 20/3425 (2013.01); B01J 20/3475 (2013.01); C07K 1/22 (2013.01); C07K 7/08 (2013.01); C07K 14/31 (2013.01); C07K 16/065 (2013.01)] 18 Claims
OG exemplary drawing
 
1. An immunofiber composition comprising one or more immuno-amphiphiles, wherein said immuno-amphiphiles comprise an antibody binding peptide conjugated to a hydrocarbon chain; and wherein the antibody binding peptide comprises a hydrophilic amino acid sequence of the Z33 peptide of Protein A of Staphylococcus aureus or an antibody-binding fragment of Z33.