US 11,745,028 B2
Systems and methods for design and fabrication of surface brachytherapy applicators
Christopher Majcher, Dartmouth (CA); Borko Basaric, Halifax (CA); and James L. Robar, Halifax (CA)
Assigned to ADAPTIIV MEDICAL TECHNOLOGIES, INC., Hallifax (CA)
Filed by ADAPTIIV MEDICAL TECHNOLOGIES INC., Halifax (CA)
Filed on May 6, 2020, as Appl. No. 16/868,021.
Claims priority of provisional application 62/875,775, filed on Jul. 18, 2019.
Prior Publication US 2021/0016106 A1, Jan. 21, 2021
Int. Cl. A61N 5/10 (2006.01); G06F 30/10 (2020.01); B33Y 80/00 (2015.01); B33Y 50/00 (2015.01); B29C 64/386 (2017.01); B29L 31/00 (2006.01); G06Q 50/04 (2012.01)
CPC A61N 5/1028 (2013.01) [B29C 64/386 (2017.08); B33Y 50/00 (2014.12); G06F 30/10 (2020.01); A61N 2005/1021 (2013.01); B29L 2031/753 (2013.01); B33Y 80/00 (2014.12); G06Q 50/04 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method of generating a digital model of a custom surface brachytherapy applicator, the method comprising:
a) obtaining an initial digital surface brachytherapy applicator model, wherein the initial digital surface brachytherapy applicator model comprises a patient-facing surface;
b) identifying a cut plane for bisecting the initial digital surface brachytherapy applicator model;
c) processing the initial digital surface brachytherapy applicator model to incorporate a plurality of catheter channels, thereby obtaining a modified digital surface brachytherapy applicator model, wherein the plurality of catheter channels are incorporated such that:
a first set of catheter channels are spatially distributed, relative to the cut plane, on a first side of the cut plane; and
a second set of catheter channels are spatially distributed, relative to the cut plane, on a second side of the cut plane;
wherein the cut plane is identified by:
processing the initial digital surface brachytherapy applicator model to determine, for each trial cut plane of a plurality of trial cut planes, a curvature measure associated with a curve defined by an intersection of the trial cut plane with the patient-facing surface of the initial digital surface brachytherapy applicator model; and
selecting the trial cut plane for which the curvature measure satisfies curvature criteria.