US 11,745,013 B2
Method and system for treating movement disorders
Pin Chang, Hsinchu (TW); Hsin Chen, Hsinchu (TW); Yen-Chung Chang, Hsinchu (TW); and Shih-Rung Yeh, Hsinchu (TW)
Assigned to BIOPRO SCIENTIFIC CO., LTD., Hsinchu (TW); and NATIONAL TSING HUA UNIVERSITY, Hsinchu (TW)
Filed by BIOPRO SCIENTIFIC CO., LTD., Hsinchu (TW); and NATIONAL TSING HUA UNIVERSITY, Hsinchu (TW)
Filed on May 19, 2020, as Appl. No. 16/877,493.
Claims priority of provisional application 62/850,317, filed on May 20, 2019.
Prior Publication US 2020/0368530 A1, Nov. 26, 2020
Int. Cl. A61N 1/36 (2006.01); A61N 2/00 (2006.01); A61N 7/00 (2006.01)
CPC A61N 1/36067 (2013.01) [A61N 1/36139 (2013.01); A61N 2/006 (2013.01); A61N 7/00 (2013.01); A61N 2007/0026 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method for treating Parkinson's disease, comprising:
recording a central nervous signal of a patient with Parkinson's disease;
identifying an onset of an oscillation episode from the central nervous signal, wherein the oscillation episode is a High-Voltage Spindle (HVS) signal having an oscillation frequency in a range of from about 5 Hz to about 13 Hz;
delivering a first stimulation from a stimulator to the patient when the onset of the oscillation episode is identified from the central nervous signal, wherein the first stimulation is applied during a course of the oscillation episode, and the first stimulation is terminated when the HVS signal is decaying to a lower threshold, terminated, or after the HVS signal being terminated for 1.0 to 2.0 seconds; and
adapting the first stimulation according to a measurable feature of the oscillation episode.