US 11,744,917 B2
Tissular formulation or adhesive obtained from a blood composition containing platelets, and method for the preparation of said formulation
Eduardo Anitua Aldecoa, Vitoria (ES)
Assigned to BIOTECHNOLOGY INSTITUTE, I MAS D, S.L., Vitoria (ES)
Filed by BIOTECHNOLOGY INSTITUTE, I MAS D, S.L., Vitoria (ES)
Filed on Feb. 11, 2020, as Appl. No. 16/787,190.
Claims priority of application No. ES201930106 (ES), filed on Feb. 11, 2019.
Prior Publication US 2020/0254138 A1, Aug. 13, 2020
Int. Cl. A61L 24/10 (2006.01); A61L 24/00 (2006.01); A61L 24/04 (2006.01)
CPC A61L 24/106 (2013.01) [A61L 24/0015 (2013.01); A61L 24/043 (2013.01); A61L 2300/414 (2013.01)] 11 Claims
 
1. A method for the preparation of an adhesive formulation from an initial blood composition, comprising:
a) obtaining an initial blood composition, of human or animal origin, containing platelets;
b) raising the temperature of the initial blood composition to a temperature of 40 to 53° C.; and
c) activating the platelets and forming a fibrin-containing
formulation comprising a fibrin clot with a coagulation time lower than 4.5 minutes.