CPC A61K 35/747 (2013.01) [A23L 33/135 (2016.08); A61K 9/0031 (2013.01); A61K 9/0053 (2013.01); A61P 25/22 (2018.01)] | 17 Claims |
1. A composition comprising a genetically engineered Bacteroides ovatus comprising a loss-of-function mutation in a gene encoding tyrosine ammonia lyase (BO1194), wherein the genetically engineered Bacteroides ovatus is deficient in the production of p-coumaric acid, relative to the same Bacteroides ovatus that is not genetically engineered.
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