CPC A61K 31/557 (2013.01) [A61K 9/0075 (2013.01); A61K 9/4858 (2013.01); A61K 31/5575 (2013.01); A61P 9/12 (2018.01); A61K 47/02 (2013.01); A61K 47/183 (2013.01); A61K 47/26 (2013.01)] | 21 Claims |
1. A system for treating pulmonary arterial hypertension, the system comprising:
a dry powder inhaler; and
a dose of dry powder particles comprising treprostinil or a pharmaceutically acceptable salt thereof, and an excipient matrix;
wherein the dry powder particles are formed from a solution comprising a pH modifying agent and a bulking agent;
wherein the dry powder particles are filled into one or more dosage units configured to be inserted into the dry powder inhaler for administration to a patient; and
wherein the one or more dosage units include a total predetermined amount of the treprostinil or the pharmaceutically acceptable salt thereof in the range of 100 μg to 350 μg.
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