US 11,744,589 B2
Devices and methods for providing passage between heart chambers
Tamir Ben-David, Tel Aviv (IL); Neal Eigler, Agoura Hills, CA (US); Nir Nae, Binjamina (IL); Lior Rosen, Or Akiva (IL); Erez Rozenfeld, Shoham (IL); and James S. Whiting, Los Angeles, CA (US)
Assigned to V-Wave Ltd., Caesarea (IL)
Appl. No. 16/963,139
Filed by V-Wave Ltd., Caesarea (IL)
PCT Filed Jan. 19, 2019, PCT No. PCT/IB2019/050452
§ 371(c)(1), (2) Date Jul. 17, 2020,
PCT Pub. No. WO2019/142152, PCT Pub. Date Jul. 25, 2019.
Claims priority of provisional application 62/619,748, filed on Jan. 20, 2018.
Prior Publication US 2021/0121179 A1, Apr. 29, 2021
Int. Cl. A61B 17/11 (2006.01); A61B 17/00 (2006.01)
CPC A61B 17/11 (2013.01) [A61B 17/0057 (2013.01); A61B 2017/00022 (2013.01); A61B 2017/00084 (2013.01); A61B 2017/00106 (2013.01); A61B 2017/00243 (2013.01); A61B 2017/00358 (2013.01); A61B 2017/00592 (2013.01); A61B 2017/00606 (2013.01); A61B 2017/00623 (2013.01); A61B 2017/1107 (2013.01); A61B 2017/1139 (2013.01); A61B 2562/0247 (2013.01)] 21 Claims
OG exemplary drawing
 
1. A device for providing a passage between a first heart chamber and a second heart chamber, the device comprising:
a middle region having first and second ends, a lumen extending therethrough, and a longitudinal axis aligned with the lumen;
a first end region coupled to the first end, the first end region configured to be delivered in the first heart chamber in a compressed delivery state and to transition to a deployed state therein, first selected portions of the first end region are configured to be independently, selectively deformable by a first force such that the first end region is expandable to different angles relative to the longitudinal axis and maintained at the different angles upon release of the first force; and
a second end region coupled to the second end, the second end region configured to be delivered in the second heart chamber in a compressed delivery state and to transition to a deployed state therein, second selected portions of the second end region are configured to be independently, selectively deformable by a second force such that the second end region is expandable to different angles relative to the longitudinal axis and maintained at the different angles upon release of the second force,
wherein the first and second end regions are configured to anchor the middle region within a heart wall between the first heart chamber and the second heart chamber, and
wherein the different angles of the first and second end regions are selected to change a blood flow rate through the passage defined by the lumen to change a coefficient of discharge of the device.