US 11,733,155 B2
Systems and methods for panel design in flow cytometry
Michael Kapinsky, Pollenried (DE)
Assigned to Beckman Coulter, Inc., Brea, CA (US)
Filed by Beckman Coulter, Inc., Brea, CA (US)
Filed on Nov. 1, 2019, as Appl. No. 16/671,795.
Application 16/671,795 is a division of application No. 14/776,891, granted, now 10,502,678, previously published as PCT/US2014/029400, filed on Mar. 14, 2014.
Claims priority of provisional application 61/791,492, filed on Mar. 15, 2013.
Prior Publication US 2020/0132594 A1, Apr. 30, 2020
Int. Cl. G01N 15/14 (2006.01); G01N 21/25 (2006.01); G01N 15/00 (2006.01); G01N 15/10 (2006.01)
CPC G01N 21/255 (2013.01) [G01N 15/14 (2013.01); G01N 15/1425 (2013.01); G01N 15/1434 (2013.01); G01N 2015/0065 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/1402 (2013.01); G01N 2015/1477 (2013.01); G01N 2201/12 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A method for determining an optimized probe panel for differentiating populations of particles in a sample using an antibody database module, the method comprising:
receiving, via a user interface, user input corresponding to one or more parameters of a probe panel, the one or more parameters including a set of antibodies corresponding to an antigenic expression pattern;
determining, via a processor, the optimized probe panel based on the user input, the determining comprising:
running a simulation of probe panels that satisfy the user input including determining a detection limit for each of one or more detection channels based on the antigenic expression pattern;
generating the optimized probe panel based on the detection limit;
retrieving, via the antibody database module, part information associated with the optimized probe panel; and
displaying, via the user interface, the part information.