CPC C12Q 1/6893 (2013.01) [C12Q 2600/118 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/16 (2013.01); G01N 2333/445 (2013.01); Y02A 50/30 (2018.01)] | 14 Claims |
1. A kit for detecting a Plasmodium infection or for genotyping Plasmodium, comprising:
a probe for detection of at least one non-synonymous SNP within a mutated K-13 propeller nucleic acid that encodes a mutated K13 propeller protein;
wherein the probe comprises a fluorescent, radioactive or enzymatic label;
wherein the protein mutation is a difference in an amino acid residue resulting from said non-synonymous SNP; and
wherein the at least one non-synonymous SNP is selected from:
G449A ggt/gct,
N458Y aat/tat,
A481V gct/gtt,
Y493H tac/cac,
R539T aga/aca,
I543T att/act,
P553L ccg/ctg,
R561H cgt/cat,
V568G gtg/ggg,
P574L cct/ctt,
C580Y tgt/tat, and
D584V gat/gtt.
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