US 11,732,301 B2
Hybrid nanopore sensors
Boyan Boyanov, San Diego, CA (US); Jeffrey G Mandell, San Diego, CA (US); Kevin L Gunderson, San Diego, CA (US); Jingwei Bai, San Diego, CA (US); Liangliang Qiang, San Diego, CA (US); and Bradley Baas, Madison, WI (US)
Assigned to Illumina, Inc., San Diego, CA (US)
Filed by Illumina, Inc., San Diego, CA (US)
Filed on Mar. 1, 2021, as Appl. No. 17/188,193.
Application 17/188,193 is a division of application No. 16/707,554, filed on Dec. 9, 2019, granted, now 10,961,576.
Application 16/707,554 is a continuation of application No. 15/522,987, granted, now 10,519,499, issued on Dec. 31, 2019, previously published as PCT/US2015/042680, filed on Jul. 29, 2015.
Claims priority of provisional application 62/157,749, filed on May 6, 2015.
Claims priority of provisional application 62/031,762, filed on Jul. 31, 2014.
Prior Publication US 2021/0269877 A1, Sep. 2, 2021
Int. Cl. C12Q 1/6874 (2018.01); G01N 33/487 (2006.01); G01N 27/447 (2006.01)
CPC C12Q 1/6874 (2013.01) [G01N 27/44782 (2013.01); G01N 27/44791 (2013.01); G01N 33/48721 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A detection apparatus comprising
(a) a plurality of electrodes; and
(b) a plurality of protein nanopores, each of the protein nanopores tethered to an electrode of the plurality of electrodes via a first tether; and
(c) a membrane surrounding each of the nanopores, wherein the membrane comprises a lipid bilayer.