CPC A61L 29/16 (2013.01) [A61K 31/337 (2013.01); A61K 31/439 (2013.01); A61L 29/08 (2013.01); A61P 31/00 (2018.01); A61P 37/06 (2018.01); A61L 2300/416 (2013.01); A61M 25/10 (2013.01); A61M 2025/105 (2013.01)] | 22 Claims |
1. A method of treating a gastrointestinal or biliary tract stricture, the method comprising:
providing a soaked balloon catheter in the gastrointestinal or biliary tract stricture, the balloon catheter comprising a balloon and a coating layer overlying an external surface of the balloon, the coating layer comprising a hydrophobic therapeutic agent and one or more water-soluble additives, wherein
the balloon catheter is soaked outside the body with a soaking solution comprising water or saline, or
the balloon catheter is soaked in the stricture with a flushing solution comprising water or saline, or
a combination thereof;
inflating the balloon so that the coating layer contacts walls of the stricture and the therapeutic agent is delivered to the walls of the stricture;
deflating the balloon after an inflation period; and
withdrawing the balloon catheter from the stricture.
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