US 11,730,864 B2
Drug coated balloon catheters for nonvascular strictures
Lixiao Wang, Henderson, NV (US); and Peter Barnett, Shakopee, MN (US)
Assigned to Urotronic, Inc., Plymouth, MN (US)
Filed by Urotronic, Inc., Plymouth, MN (US)
Filed on Jan. 17, 2023, as Appl. No. 18/97,690.
Application 18/097,690 is a continuation of application No. 17/951,321, filed on Sep. 23, 2022.
Application 17/951,321 is a continuation of application No. 17/107,136, filed on Nov. 30, 2020, granted, now 11,484,628.
Application 17/107,136 is a continuation of application No. 15/568,614, granted, now 10,888,640, previously published as PCT/US2016/028652, filed on Apr. 21, 2016.
Claims priority of provisional application 62/152,559, filed on Apr. 24, 2015.
Prior Publication US 2023/0149602 A1, May 18, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61L 29/16 (2006.01); A61P 31/00 (2006.01); A61P 37/06 (2006.01); A61K 31/337 (2006.01); A61K 31/439 (2006.01); A61L 29/08 (2006.01); A61M 25/10 (2013.01)
CPC A61L 29/16 (2013.01) [A61K 31/337 (2013.01); A61K 31/439 (2013.01); A61L 29/08 (2013.01); A61P 31/00 (2018.01); A61P 37/06 (2018.01); A61L 2300/416 (2013.01); A61M 25/10 (2013.01); A61M 2025/105 (2013.01)] 22 Claims
OG exemplary drawing
 
1. A method of treating a gastrointestinal or biliary tract stricture, the method comprising:
providing a soaked balloon catheter in the gastrointestinal or biliary tract stricture, the balloon catheter comprising a balloon and a coating layer overlying an external surface of the balloon, the coating layer comprising a hydrophobic therapeutic agent and one or more water-soluble additives, wherein
the balloon catheter is soaked outside the body with a soaking solution comprising water or saline, or
the balloon catheter is soaked in the stricture with a flushing solution comprising water or saline, or
a combination thereof;
inflating the balloon so that the coating layer contacts walls of the stricture and the therapeutic agent is delivered to the walls of the stricture;
deflating the balloon after an inflation period; and
withdrawing the balloon catheter from the stricture.