	US 11,730,791 B2
	Therapeutic method of treatment for inhibiting tumor development using Tamm-Horsfall glycoprotein (THP) as immunostimulating drug and compositions
Miguel Angel Castellano, Montevideo (UY); José F. Groisman, Buenos Aires (AR); Liliana Ester Balanian, Buenos Aires (AR); Felipe Inserra, Buenos Aires (AR); Emilio Sojo, Prov. de Buenos Aires (AR); Claudio Fernando Wolfenson Band, Buenos Aires (AR); and Elena M. V. de Cavanagh, Martínez (AR)
Assigned to INSTITUTO MASSONE S.A., Buenos Aires (AR); and Raäl Enrique Massone, Buenos Aires (AR)
Filed by INSTITUTO MASSONE S.A., Buenos Aires (AR); and Raúl Enrique Massone, Buenos Aires (AR)
Filed on Oct. 12, 2021, as Appl. No. 17/450,613.
Application 17/450,613 is a division of application No. 15/204,033, filed on Jul. 7, 2016, granted, now 11,167,009.
Application 15/204,033 is a division of application No. 14/377,575, abandoned, previously published as PCT/IB2013/051053, filed on Feb. 8, 2013.
Claims priority of provisional application 61/596,863, filed on Feb. 9, 2012.
Prior Publication US 2022/0031805 A1, Feb. 3, 2022
Int. Cl. A61K 38/17 (2006.01); A61K 38/16 (2006.01); A61P 35/00 (2006.01)

CPC A61K 38/1709 (2013.01) [A61K 38/16 (2013.01); A61P 35/00 (2018.01); Y02A 50/30 (2018.01)]

2 Claims

1. A therapeutic method of treatment of colon cancer in a mammal, wherein the colon cancer has intratumor vascularization and the intratumor vascularization is retained after the therapeutic treatment, the method comprising parenterally administering to a mammal in need thereof a composition comprising an effective amount of human Tamm-Horsfall glycoprotein, native or pegylated, and a pharmacologically acceptable excipient.