CPC A61K 35/747 (2013.01) [C12N 1/205 (2021.05); A61K 2035/115 (2013.01); C12R 2001/225 (2021.05)] | 18 Claims |
1. A method for treating or reducing the risk of developing a condition or disorder caused by or related to an ethanolamine-utilizing pathogen in a subject in need thereof, said method comprising administering to the subject an effective amount of lactic acid bacteria capable of utilizing ethanolamine produced by
(a) culturing in a culture medium lactic acid bacteria that comprises a gene encoding ethanolamine ammonia lyase large subunit EutB, a gene encoding a microcompartment structural protein EutL, and/or a gene encoding an ethanolamine utilization protein EutH and is capable of utilizing ethanolamine;
(b) adding to the culture medium of (a) a first amount or concentration of ethanolamine at a first point in time and growing said culture;
(c) optionally adding to the culture of (b) a second amount or concentration of ethanolamine at a second point in time and growing said culture; and
(d) retrieving the lactic acid bacteria from said culture medium.
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