US 11,730,717 B1
Melanin-inspired antimicrobial
Toby Larue Nelson, Stillwater, OK (US); Santosh Adhikari, Los Alamos, NM (US); Erika Lutter, Stillwater, OK (US); and Karen Wozniak, Guthrie, OK (US)
Assigned to The Board of Regents for the Oklahoma Agricultural and Mechanical Colleges, Stillwater, OK (US)
Filed by The Board of Regents for the Oklahoma Agricultural and Mechanical Colleges, Stillwater, OK (US)
Filed on Jul. 13, 2021, as Appl. No. 17/374,535.
Claims priority of provisional application 63/052,033, filed on Jul. 15, 2020.
Int. Cl. A61K 31/404 (2006.01); A61K 31/04 (2006.01); A61K 31/10 (2006.01); A01N 43/38 (2006.01); A61P 31/04 (2006.01); A61P 31/10 (2006.01)
CPC A61K 31/404 (2013.01) [A01N 43/38 (2013.01); A61P 31/04 (2018.01); A61P 31/10 (2018.01)] 19 Claims
 
1. A melanin-based antimicrobial of Formula I:

OG Complex Work Unit Chemistry
wherein
R1, R2, R3, and R4 are independently the same or different and are alkyl, alkenyl, alkynyl, cycloalkyl, aryl, perfluoroalkyl, a heterocyclic amine or a quaternary ammonium salt;
L is a linker comprising 1-6 carbon atoms;
A is a halogen, a carboxylic acid anion or an inorganic anion; and
n=1-10.