US 11,730,697 B2
Ocular drug delivery devices
Jean Theresa Jacob, New Orleans, LA (US); Kevin John Halloran, Somerset, NJ (US); and Yuri McKee, Atlanta, GA (US)
Assigned to Bausch Health Americas, Inc., Bridgewater, NJ (US); and Louisiana State University Agricultural and Mechanical College, Baton Rouge, LA (US)
Filed by Bausch Health Americas, Inc., Bridgewater, NJ (US); and Louisiana State University Agricultural and Mechanical College, Baton Rouge, LA (US)
Filed on Jan. 7, 2019, as Appl. No. 16/241,558.
Application 16/241,558 is a division of application No. 14/087,864, filed on Nov. 22, 2013, abandoned.
Application 14/087,864 is a continuation of application No. 12/916,398, filed on Oct. 29, 2010, abandoned.
Claims priority of provisional application 61/391,040, filed on Oct. 7, 2010.
Claims priority of provisional application 61/256,915, filed on Oct. 30, 2009.
Prior Publication US 2019/0133934 A1, May 9, 2019
Int. Cl. A61K 9/00 (2006.01); A61K 31/00 (2006.01); A61K 47/36 (2006.01); C08L 1/28 (2006.01); A61K 31/133 (2006.01); A61K 31/216 (2006.01); A61K 31/7036 (2006.01); A61K 38/12 (2006.01); A61K 38/13 (2006.01)
CPC A61K 9/0051 (2013.01) [A61K 31/00 (2013.01); A61K 31/133 (2013.01); A61K 31/216 (2013.01); A61K 31/7036 (2013.01); A61K 38/12 (2013.01); A61K 38/13 (2013.01); A61K 47/36 (2013.01); C08L 1/284 (2013.01)] 20 Claims
 
1. A method of forming an ocular delivery device comprising:
placing a solid, shaped cellulose polymer in a vessel adapted to restrict the swelling of the polymer in at least one direction;
exposing the solid, shaped cellulose polymer, while in said vessel, to a solution comprising an active pharmaceutical ingredient and a solvent capable of solubilizing said active pharmaceutical ingredient, wherein the polymer absorbs at least a portion of the solution, including the active pharmaceutical ingredient and solvent;
allowing the absorbed solvent to evaporate from the polymer or drying the polymer; and
freeing the polymer from the vessel.