US 11,730,561 B2
Apparatus and methods for three-dimensional printed oral stents for head and neck radiotherapy
Eugene Jon Koay, Houston, TX (US); Caroline Chung, Houston, TX (US); Christopher T. Wilke, Houston, TX (US); Clifton David Fuller, Houston, TX (US); and Mohamed Zaid, Houston, TX (US)
Assigned to Board of Regents, The University of Texas System, Austin, TX (US)
Appl. No. 16/631,662
Filed by Board of Regents, The University of Texas System, Austin, TX (US)
PCT Filed Jul. 17, 2018, PCT No. PCT/US2018/042364
§ 371(c)(1), (2) Date Jan. 16, 2020,
PCT Pub. No. WO2019/018322, PCT Pub. Date Jan. 24, 2019.
Claims priority of provisional application 62/533,321, filed on Jul. 17, 2017.
Prior Publication US 2020/0170749 A1, Jun. 4, 2020
Int. Cl. G06T 15/00 (2011.01); A61B 90/16 (2016.01); B33Y 10/00 (2015.01); B33Y 50/00 (2015.01); B33Y 80/00 (2015.01); A61N 5/10 (2006.01); A61B 6/03 (2006.01); A61C 9/00 (2006.01)
CPC A61B 90/16 (2016.02) [A61N 5/10 (2013.01); B33Y 10/00 (2014.12); B33Y 50/00 (2014.12); B33Y 80/00 (2014.12); A61B 6/032 (2013.01); A61C 9/0046 (2013.01); A61N 2005/1097 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A method of manufacturing a patient-specific oral stent for head and neck radiotherapy, the method comprising:
segmenting a bony anatomy of an oral cavity of a patient;
simulating movement of a jaw of the patient;
opening the jaw to a specified distance between a top reference point and a bottom reference point;
creating a digital negative impression of the bony anatomy when the jaw is opened to the specified distance;
transforming the digital negative impression into a digital oral stent, wherein transforming the digital negative impression into the digital oral stent comprises adding tissue-displacing surfaces to the digital negative impression and wherein the tissue-displacing surfaces comprise a surface configured to provide tongue lateralization;
translating the digital oral stent into a printable file; and
printing the printable file via a three-dimensional (3D) printer to create the patient-specific oral stent.