US 11,726,159 B2
B0 and B1 correction anti-respectively
Yi-Cheng Hsu, Taipei (TW); and Patrick Liebig, Erlangen (DE)
Assigned to Siemens Healthcare GmbH, Erlangen (DE)
Filed by Siemens Healthcare GmbH, Erlangen (DE)
Filed on Jun. 9, 2021, as Appl. No. 17/343,014.
Claims priority of application No. 202010526773.9 (CN), filed on Jun. 10, 2020.
Prior Publication US 2021/0389404 A1, Dec. 16, 2021
Int. Cl. G01R 33/565 (2006.01); G06T 5/50 (2006.01); G01R 33/485 (2006.01)
CPC G01R 33/56527 (2013.01) [G01R 33/485 (2013.01); G06T 5/50 (2013.01); G06T 2207/10088 (2013.01); G06T 2207/30016 (2013.01)] 11 Claims
OG exemplary drawing
 
1. A Chemical Exchange Saturation Transfer (CEST) imaging correction method, comprising:
collecting, via one or more processors, a plurality of CEST images in an imaging area;
for each pixel point in each one of the plurality of CEST images:
calculating a corresponding real saturation frequency of each respective pixel point according to (i) a predetermined frequency deviation of a water resonance frequency of the corresponding voxel of the pixel point relative to the corresponding water resonance frequency of a main magnetic field, and (ii) a frequency of a pre-saturated RF pulse used for collecting the CEST image, and
calculating the corresponding real saturation B1 field intensity of each respective pixel point according to a predetermined conversion coefficient between (i) a real saturation B1 field intensity of the corresponding voxel of the pixel point and a system B1 field intensity, and (ii) an intensity of the pre-saturated RF pulse used for collecting the CEST image,
wherein the system B1 field intensity is equal to the intensity of the pre-saturated RF pulse used for collecting the CEST image; and
for pixel points corresponding to the same voxel in an imaging area in each one of the plurality of CEST images:
comparing the corresponding real saturation frequency and real saturation B1 field intensity of each respective pixel point with (i) a target saturation frequency, and (ii) a target saturation B1 field intensity, respectively;
selecting a plurality of pixel points as interpolated pixel points according to the comparison results of the real saturation frequency and real saturation B1 field intensity; and
performing interpolation calculations for the pixel values of the selected interpolated pixel points in the plurality of CEST images to obtain a pixel value of the corresponding voxel having (i) the target saturation frequency, and (ii) the target saturation b1 field intensity.