US 11,725,176 B2
Humidity control in chemical reactors
Shireen Goh, Singapore (SG); Rajeev Jagga Ram, Arlington, MA (US); Kevin Shao-Kwan Lee, Cambridge, MA (US); Michelangelo Canzoneri, Dusseldorf (DE); and Horst Blum, Kriftel (DE)
Assigned to Sanofi, Paris (FR); and Massachusetts Institute Of Technology, Cambridge, MA (US)
Filed by Sanofi, Paris (FR); and Massachusetts Institute of Technology, Cambridge, MA (US)
Filed on Aug. 29, 2022, as Appl. No. 17/897,489.
Application 17/897,489 is a division of application No. 16/654,808, filed on Oct. 16, 2019, granted, now 11,459,538.
Application 16/654,808 is a division of application No. 14/064,021, filed on Oct. 25, 2013, granted, now 10,472,602, issued on Nov. 12, 2019.
Claims priority of provisional application 61/869,118, filed on Aug. 23, 2013.
Claims priority of provisional application 61/719,085, filed on Oct. 26, 2012.
Claims priority of application No. 13306464 (EP), filed on Oct. 23, 2013.
Prior Publication US 2022/0411741 A1, Dec. 29, 2022
Int. Cl. C12M 1/34 (2006.01); B01J 19/00 (2006.01); C12M 1/04 (2006.01); C12M 1/00 (2006.01)
CPC C12M 41/44 (2013.01) [B01J 19/0006 (2013.01); C12M 23/24 (2013.01); C12M 29/26 (2013.01); C12M 41/34 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A reactor system, comprising:
a reactor chamber, comprising:
a liquid sub-chamber configured to contain a liquid growth medium including at least one cell;
a gas sub-chamber configured to contain a gaseous headspace above the liquid growth medium; and
a gas-permeable flexible membrane separating the liquid sub-chamber from the gas sub-chamber;
a gas inlet conduit configured to transport gas into the gas sub-chamber through a reactor chamber gas inlet;
a gas outlet conduit configured to transport gas out of the gas sub-chamber through a reactor chamber gas outlet; and
a gas bypass conduit external to the reactor chamber, connecting the gas inlet conduit to the gas outlet conduit.