	US 11,725,118 B2
	Method for the preparation of gelatin hydrolysate having a low endotoxin content
Joseph Hubertus Olijve, Ghent (BE); Eline Bakhuizen, Ghent (BE); and Paul Stevens, Ghent (BE)
Assigned to Rousselot BVBA, Ghent (BE)
Appl. No. 16/766,654
Filed by Rousselot BVBA, Ghent (BE)
PCT Filed Nov. 22, 2018, PCT No. PCT/EP2018/082238 § 371(c)(1), (2) Date May 22, 2020, PCT Pub. No. WO2019/101864, PCT Pub. Date May 31, 2019.
Claims priority of application No. 17203341 (EP), filed on Nov. 23, 2017.
Prior Publication US 2020/0362201 A1, Nov. 19, 2020
Int. Cl. C09H 3/02 (2006.01); C08L 89/06 (2006.01); A61K 8/65 (2006.01)

CPC C09H 3/02 (2013.01) [C08L 89/06 (2013.01)]

9 Claims

1. A method for the preparation of a gelatin hydrolysate having a decreased endotoxin content, comprising the steps of:

a) incubating a solution of gelatin or gelatin hydrolysate at a temperature of 80-96° C. at a pH of 3.5 or less for a time period of at least 15 minutes, and

b) recovering the gelatin hydrolysate having a decreased endotoxin content,

wherein in the method, no surfactant is added to the gelatin or gelatin hydrolysate.