CPC C07K 16/32 (2013.01) [C07K 2317/51 (2013.01); C07K 2317/54 (2013.01); C07K 2317/55 (2013.01); C07K 2317/567 (2013.01); C07K 2317/569 (2013.01); C07K 2317/622 (2013.01)] | 12 Claims |
1. A method for improving affinity of an antibody or an antibody fragment for an antigen, comprising improving affinity of the antibody or the antibody fragment by changing 3rd, 5th and 9th amino acid residues defined by Kabat method of a light chain of the antibody or the antibody fragment to charged amino acid residues.
|