CPC C07K 16/2803 (2013.01) [A61K 2039/505 (2013.01); A61K 2039/545 (2013.01); C07K 2317/21 (2013.01); C07K 2317/32 (2013.01); C07K 2317/34 (2013.01); C07K 2317/41 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/622 (2013.01); C07K 2317/626 (2013.01); C07K 2317/72 (2013.01); C07K 2317/732 (2013.01); C07K 2317/92 (2013.01)] | 22 Claims |
1. A CD83 binding protein comprising an antigen binding domain which binds to CD83, wherein the CD83 binding protein comprises:
(a) a heavy chain variable region (VH) which comprises:
three complementarity determining regions (CDRs) of the amino acid sequence shown in SEQ ID NO: 1; and
(b) a light chain variable region (VL) which comprises:
(i) three complementarity determining regions (CDRs) of any one of the amino acid sequence shown in SEQ ID NO: 5, 6, 7, 8, or 9;
(ii) a consensus sequence as shown in SEQ ID NO: 10; or
(iii) three CDRs, wherein the amino acid sequence of CDR1, CDR2, or CDR3 is a consensus sequence shown in SEQ ID NO: 26, 27 or 28.
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