	US 11,725,039 B2
	α/β t-cell receptor and methods of using it
Andrew Sewell, Cardiff South Glamorgan (GB); and Garry Dolton, Cardiff South Glamorgan (GB)
Assigned to University College Cardiff Consultants Ltd., Cardiff (GB)
Filed by University College Cardiff Consultants Ltd., Cardiff South Glamorgan (GB)
Filed on Apr. 24, 2020, as Appl. No. 16/858,082.
Application 16/858,082 is a continuation in part of application No. PCT/GB2018/053045, filed on Oct. 22, 2018.
Prior Publication US 2020/0369742 A1, Nov. 26, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 14/725 (2006.01); A61K 35/17 (2015.01); A61K 45/06 (2006.01); C12N 7/00 (2006.01); A61K 38/00 (2006.01)

CPC C07K 14/7051 (2013.01) [A61K 35/17 (2013.01); A61K 45/06 (2013.01); C12N 7/00 (2013.01); A61K 38/00 (2013.01); C12N 2740/15043 (2013.01)]

10 Claims

1. A vector encoding a T-cell receptor (TCR) wherein the TCR comprises

(i) an α chain that comprises the CDR1α, CDR2α, and CDR3α amino acid sequences of the α chain amino acid sequence set forth in SEQ ID NO: 7; and

(ii) a β chain that comprises the CDR1β, CDR2β, and CDR3β amino acid sequences of the β chain amino acid sequence set forth in SEQ ID NO: 8.